Innovation comes to Alzheimer disease.
Alzheimer’s disease (AD) is the most relevant neurodegenerative disease. Worldwide, nearly 36 million people have Alzheimer’s or a related dementia which will double every 20 years to 115.4 million in 2050, and in Europe affects about 7.5 million people (75% of all dementia cases) and is expected to increase up to 10.5 million in 2030, with a reported prevalence rate of 6.2% for all those aged 60 years and over. Only 1-in-4 people with AD have been diagnosed. For the fast ageing populations of the Western societies, AD is becoming one of the main public health concerns, associated with a social and economic burden, and the provision of care for people with AD is a complex and costly issue. At present, there is not any therapy that can effectively cure the disease since it is a complex disorder of which the exact cause is still not known.
The aproach to Alzheimer´s disease is changing gloabally. Oncovision’s plan, is to develop a new brain-dedicated PET that offers a valuable alternative to currently available whole-body PET systems.
Caremibrain fulfils the necessities of neurologists and nuclear physicists regarding the β-amyloid radiotracers and the firsts true effective drugs against Alzheimer disease in its final development stage (Aducanumab –Biogen–; Azeliragon –Pfizer–; Gantenerumab –Roche–, Solanezumab –Eli Lilly–, Verubecestat –Merck–).
CareMiBrain, the Oncovision brain dedicated PET, recently passed all the electromagnetic compatibility trials through an independent certified laboratory, according to the international regulation IEC 60601-1-2 for electro medical devices. The technology is electromagnetically compatible, so it works alongside other medical devices without causing interference.
EMC certification allows Oncovision to continue development of CareMiBrain as scheduled, beginning with a pilot study beginning in the third quarter of 2017 when a referenced medical center will install CareMiBrain.
The Clinical trials in EU will take place beginning of December 2017, at the University Hospital of Tübingen (Germany) and the Karolinska Institutet (Sweden).
The Clinical trials in USA will take place beginning of April 2018, at Massachusetts General Hospital (Boston, MA) and Northern California PET Imaging Center (Sacramento, CA).
Very high resolution.
Its impressive resolution (under 2mm in all the FOV) and higher sensitivity generates high quality images with outstanding Signal/Noise ratio that could be used by doctors for reducing significantly the number of difficult to diagnose cases.
More patients studied per day.
At the same time, the higher sensitivity of the system allows to use a lower radiotracer dose and reducing scanning duration time, increasing the number of patients studied per day, their safety and comfort.
The small size of the equipment will allow physicians to us the technology in many clinics where large Medical devices can´t be install.
A dedicated Brain PET for Neurological patients will give an accurate image to determinate AD´s disease.